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Year : 2018  |  Volume : 11  |  Issue : 5  |  Page : 447-448

Isoniazid-induced acute pancreatitis in a child with tuberculous meningitis

Department of Pediatric Gastroenterology and Hepatology, BJ Wadia Hospital for Children, Mumbai, Maharashtra, India

Correspondence Address:
Himali Meshram
54, Om Adarshaniya Housing Society, Harihar Nagar, Beltarodi Road, Besa, Nagpur - 440 037, Maharashtra
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Source of Support: None, Conflict of Interest: None


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Drug-related acute pancreatitis is uncommon in children and is mostly caused due to valproic acid, l-asparaginase, prednisone, and 6-mercaptopurine. Anti-tuberculous drugs causing pancreatitis are rare. We present a 3-year-old girl with tuberculous meningitis who developed isoniazid (INH)-induced pancreatitis. She has persistent vomiting in spite of omission of steroids and ultrasound showed bulky pancreas with high serum amylase. Her vomiting subsided with the omission of INH.

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