|Year : 2021 | Volume
| Issue : 1 | Page : 13
Vitamin D, antiviral agent, and COVID-19
Depatment of Community Medicine, Dr. DY Patil University, Pune, Maharashtra, India; Department of Tropical Medicine, Hainan Medical University, Haikou, China
|Date of Submission||22-Jun-2020|
|Date of Decision||05-Jul-2020|
|Date of Acceptance||30-Jul-2020|
|Date of Web Publication||22-Jan-2021|
Depatment of Community Medicine, Dr. DY Patil University, Pune, Maharashtra
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Wiwanitkit V. Vitamin D, antiviral agent, and COVID-19. Med J DY Patil Vidyapeeth 2021;14:13
Vitamin is a necessary trace element for human beings. Human requires a few amount of vitamin, but it has to be intake. The role of vitamin in homeostasis and regulations of the physiological process in the human bond is important. In clinical nutrition, several advantages of vitamin are purposed. The role of vitamin in infectious disease management is very interesting. Vitamin plays might play a role in infectious disease management by both direct and infect mechanisms. The publication in the journal on “Vitamin D as an Antiviral Agent” is interesting. According to the present new emerging coronavirus crisis, medical scientists have tried best to find the alternative new therapy for disease containment since its first emergence.
Vitamin is an alternative that is mentioned. Of several vitamins, Vitamin D is widely proposed for its usefulness. Basically, Vitamin D is a nonwater soluble vitamin and biosynthesis after sunlight exposure is possible in the human body. A good example is a recent report on the immunomodulation effect for the treatment of epidemic diarrheal virus infection in the animal model. Regarding the new emerging COVID-19, there is still no clinical trial on the therapeutic/preventive effect of Vitamin D. There are some observational reports on the clinical association. In a recent report from the UK, low Vitamin D status was associated with the risk of severe COVID-19. It is proposed that Vitamin D deficiency might increase the severity of COVID-19.
Based on the mentioned observations, some medical scientists believe that Vitamin D might be an alternative drug for the management of COVID-19. Vitamin D receptor stimulation is believed to be an important pharmacophysiological process of Vitamin D that might be beneficial for the management of COVID-19. Nevertheless, the role of Vitamin D receptor and its genetic polymorphisms in vitamin-related mechanisms for the management of the infectious disease is still unknown at present. There are also confounding factors that it can still not conclude for the exact association between Vitamin D and COVID-19. The high incidence of COVID-19 is still reported from tropical countries where there is no problem of Vitamin D deficiency among the local population. Since there is still no standard treatment or vaccine for the management of COVID-19, the use of Vitamin D for COVID-19 management, which is a nutrition, might be an interesting clinical research issue.
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