|LETTER TO THE EDITOR
|Year : 2022 | Volume
| Issue : 6 | Page : 953
Thyroid profile in idiopathic childhood steroid-sensitive nephrotic syndrome
Mahmood D Al-Mendalawi
Department of Paediatrics, Al-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq
|Date of Submission||24-Dec-2021|
|Date of Decision||10-Feb-2022|
|Date of Acceptance||21-Mar-2022|
|Date of Web Publication||01-Jun-2022|
Prof. Mahmood D Al-Mendalawi
P.O. Box 55302, Baghdad Post Office, Baghdad
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Al-Mendalawi MD. Thyroid profile in idiopathic childhood steroid-sensitive nephrotic syndrome. Med J DY Patil Vidyapeeth 2022;15:953
In the November-December 2021 issue of the Medical Journal of Dr. D.Y. Patil Vidyapeeth, Nandi et al. studied thyroid status in a cohort of Indian children with steroid-sensitive nephrotic syndrome (NS) during the time of relapse and remission. They found that the levels of thyroid stimulating-hormone (TSH), triiodothyronine (T3), and thyroxine (T4) significantly varied at the attack/relapse compared to at remission. While T3 and T4 levels stayed within the normal ranges, there was a rise in the TSH level at the time of the attack/relapse. Apart from the few study limitations presented by Nandi et al., we believe that the following limitation is relevant. The accurate evaluation of thyroid gland functions for a given pediatric population requires the need to refer to the thyroid hormones normative values (THNV). As THNV are determined by different factors such as age, gender, weight, and ethnicity, certain pediatric populations-specific THNV have been generated., India has already constructed THNV for each year of life for both genders separately to be utilized in the clinical fields and researches centers. In the study, methodology, Nandi et al. regrettably did not address which THNV they referred to assess thyroid condition in the studied cohort. This methodological limitation might throw further suspicions on the study findings.
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Conflicts of interest
There are no conflicts of interest.
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